IMMUNOLOGIC PROPERTIES OF MOUSE THYMUS CELLS

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Immunologic Properties of Mouse Thymus Cells

The functional attributes of minor subpopulations of mouse thymus cells derived by bovine serum albumin density gradient centrifugation, cortisone treatment, or selective depletion by anti-TL or anti-theta treatment have been examined. A subpopulation derived in each fashion contains the cells required to evoke graft-versus-host reactions in neonatal F(1) hybrid recipients and to be stimulated ...

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Mouse Thymus-independent and Thymus-derived Lymphoid Cells

The simultaneous use on mouse lymphoid suspensions of heterologous antisera directed against thymus-derived (T) cell mouse-specific lymphocyte antigen and brain-associated theta antigen (MSLA and BAtheta) or thymus-independent (B) cell mouse-specific bone marrow-derived lymphocyte antigen (MBLA) surface antigens allowed direct proof of the different specificity of these antisera by double immun...

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Characterization of thymus-seeding precursor cells from mouse bone marrow.

The nature of the cells that seed the thymus of an irradiated recipient after intravenous (IV) transfer of bone marrow (BM) cells was investigated using 2 approaches. First, direct entry of a small number of donor BM cells into the thymus was tracked using a Ly-5 marker. Second, secondary IV transfer of the seeded thymus cells into a secondary recipient was used as an assay for precursor activi...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1972

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.136.6.1461